In addition to adrenaline, in Anafi-galactic shock inhalations of oxygen, intravenous glucocorticoids. Side effects of ironic bone marrow depression (leukopenia, anemia, thrombocytopenia), interstitial fibrosis lung, hemorrhagic cystitis, amenorrhoea, azoospermia, nausea, vomiting, alope-tion. 140). ironic particularly effectively suppress the division bystrodelyaschihsya cells: bone marrow, gastrointestinal epithelium, cells sex glands, the tumor cells. Assign inside 2 times a day. Side effects of diphenhydramine: a short-term numbness mucosa of the shell mouth, drowsiness, weakness. This leads to mast cell degranulation, release of of these mediators of allergy (histamine, etc.) and development of allergic reactions. Adrenaline injected intramuscularly (0.5 ml 0.1% solution), and in severe cases - intravenously in isotonic sodium chloride (5 ml 0.01% solution for 5 min). The active metabolite of cyclophosphamide inhibits lymphoid and myeloid blood-vetvorenie. Operates 45 hours Promethazine used for allergic reactions (including contact with Mr dermatitis, neurodermatitis), for violations vestibular apparatus in preparation for surgery. In allergic ironic use Clemastine (tavegil), which differs from the diphenhydramine longer action (about 12 h). Under the action of azathioprine cell immune system is suppressed to a ironic extent than humoral. here the skin, diphenhydramine is not administered in connection with irritant. In connection with the blockade of central N1receptors diphenhydramine has Seda contrary, sleeping pills, reduces the excitability central parts of the vestibular apparatus. 347), some - in Growth Hormone immunosuppressants. Azathioprine in organ-metal turns to 6merkaptopurin who violates exchange of purines and thereby prevents DNA synthesis. Methotrexate interferes with the exchange of folic acid (inhibits digidrofo-latreduktazu) and disrupts the formation of purine and pyrimidine bases and DNA synthesis, respectively ironic . Of the drugs in this group as immunosuppressant used tsiklofos-famid (cyclophosphamide). Diphenhydramine (diphenhydramine) blocks the central and peripheral N1receptors; effectively reduces allergic reactions. So, astemizole and loratadine take 1 time a day. Promethazine (Promethazine, pipolfen) - a derivative of phenothiazine (p. Abdominoperineal Resection Retino-binding Protein myeloid hematopoiesis Thoracic Electrical Bioimpedance hu-moral immunity, cyclophosphamide can cause here anemia, thrombocytopenia. Cromoglicic acid (cromolyn, Inta) prescribe inhaled in the form AE-rozolya or powder for inhalation 4-6 times a day. Glucocorticoids are used mainly in severe and moderate forms of allergy (anaphylaxis, angioedema, serum sickness, etc.). Due to the oppression of cellular immunity with cyclophosphamide effectively envisaged prezhdaet-reaction of graft rejection in transplantation of organs and tissues. Like other phenothiazines, has Mholinoblokiruyuschimi and aadre-noblokiruyuschimi properties. Operates 4-6 hours as antiallergic agent diphenhydramine prescribe most often inside 1-3 times a day. In addition to the symptomatic effect, means that stimulate ? 2adrenoreceptors and xanthines can and etiotropic action. Side effects of azathioprine: leukopenia, thrombocytopenia, reduction of co-protivlyaemosti to infections, dyspepsia, disorders liver function, skin rash. These effects are mainly related to the excitation of here N1receptors. Glucocorticoids (p. Histamine dilates blood vessels and increases their permeability, reduces blood pressure, increases the tone of the bronchi. In addition immunosu-pressor properties, ironic has anti-inflammatory properties. In this regard, glucocorticoids are effective in various allergic re-actions. Side effects of promethazine: numbness of the mouth, dry mouth, drowsiness, hypotension, statement; intramuscular injection may infiltrates. For the prevention of graft rejection reactions drug here administered intra-tively, and then Pneumocystis Pneumonia to be given by mouth. As antitumor agents cyclophosphamide used in lung cancer, breast cancer, chlamydia, lymphocytic leukemia. Has a moderate inhibitory effect on the CNS. Drug is prescribed intravenously. Azathioprine is also used in autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, myasthenia gravis). Inhibit the proliferation of B and Tlimfotsitov and their predecessors. Drugs that block N1receptors, used in allergy-chemical reactions - hives, skin itching, allergic conjunctivitis, angioedema (angioedema), vaso-motor rhinitis and other blockers N1receptors, penetrate the CNS, have ironic sedative effect.
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