If necessary, dose may gradually increase to achieve the effect of painkillers to 1800 mg / day. Method of production of drugs: Table. Indications for use drugs: neurotic pain in adults with epilepsy (as a means of further attacks in the treatment of partial adults, with or without secondary generalization), generalized anxiety disorders in adults; fibromyalgia. Indications for use drugs: treatment of manic phase of bipolar affective disorder, prevention of relapse episodes bipolar affective disorder, and to reduce the intensity and frequency of these episodes of bellhop in patients with manic episodes in the history, prevention phase of depression in patients with affective disorder unipolyarnym. Side effects and complications in the use of drugs: psevdotumor brain, muscle tremor (tremor and atrial krupnorozmashystyy) ataxia, athetosis, increased tendon reflexes, extrapyramidal symptoms, and stool incontinence, seizures, drowsiness, dezoriyentovanist, memory disturbance, coma, visual disturbances, speech disorders, headache, arrhythmia, hypotension, syncope, bradycardia, Beck Depression Inventory node bellhop vascular insufficiency, peripheral edema, nausea, vomiting, diarrhea, abdominal pain, anorexia, swelling of the salivary glands glucosuria, decreased creatinine clearance, albuminuria, oliguria, Thrombin Time of diabetes (polyuria, polydipsia), hair loss, Not Elsewhere Specified psoriasis, itching, rash, vkryvannya ulcers, hyperkeratosis, folliculitis, dry mouth, impotence, Grave's disease, hipotyroyidyzm, hyperthyroidism, weight loss, hyperglycemia, hypercalcemia, allergic vasculitis, anemia, leukopenia, bellhop edema, taste disorder, caries, side effects Lithium caused more pronounced in older patients than in the young, despite the same concentration of lithium serum. Indications for use drugs: neurotic pain in adults in combination with other antiepileptic drugs for Treatment of partial epileptic seizures with or without secondary generalization in adults and children over 12 years of partial attacks in children aged 6 - 12 years. The main effect of pharmaco-therapeutic effects of drugs: topiramat belongs to the class sulfatzamischenyh monosaccharides, antiepileptic bellhop which caused a number of its properties - reduces the frequency of action potentials bellhop of the neuron in steady state depolarization, indicating the bellhop of blocking action of the drug on sodium channels on the state of neuron potentiates GABA activity against certain subtypes of GABA receptors (including HAMKA receptor), and modulates activity most HAMKA-receptors prevents activation kainatom sensitivity kainat / AMPK-glutamate receptor do not affect on the activity of N-Methyl-D-aspartate against bellhop Certified Registered Nurse Anesthetist for use bellhop as monotherapy for bellhop treatment of adults and bellhop over 2 years with partial epileptic seizures, primary generalized tonic-clonic seizures, as adjunctive therapy to Duchenne Muscular Dystrophy adults and children older than 2 years with partial epileptic seizures, primary generalized tonic-clonic bellhop with seizures, associated with c-IOM-Lenox Gast, bellhop of migraine in adults. Side effects and complications in the use of drugs: nervousness, dizziness, headache, disturbance of language, psychomotor retardation, ataxia, fatigue, impaired concentration of attention, difficulty remembering, confusion, drowsiness, disturbance in thinking, anorexia, nystagmus, paresthesia, depression, additional children - personality disorder, excessive salivation, hiperkineziya, breach of taste sensations, agitation, cognitive dysfunction, emotional lability, dystaxia and gait, apathy, psychosis, psychotic symptoms, aggressive reaction, bellhop rare - suicidal thoughts and attempts, hallucinations; reduce the depth of the anterior chamber of the eye, hyperemia of the eye, increased intraocular pressure, diplopia, midriaz; dyspeptic effects, nausea, abdominal pain, diarrhea, dry lips, increased hepatic transaminases, hepatitis, liver failure; reduction of body weight, asthenia, nephrolithiasis, olihohidroz (mainly in children), metabolic acidosis, fever, bahatoformna erythema, pemfihus, CM Stevens-Johnson toxic epidermal necrolysis, leucopenia, neutropenia, thrombosis. 50 mg, 100 mg, 300 mg, 400 mg cap. Pharmacotherapeutic group: N03AX11 - antiepileptic agents. Dosing and Administration of drugs: neurotic pain, epilepsy - recommended starting dose is 75 mg prehabalinu 2 p / day, regardless of the meal, the application of effective doses of 150 to 600 mg / day for most patients optimal dose is 150 mg prehabalinu 2 g bellhop day bellhop on the individual effect and sensitivity to the drug, the dose may be increased to 150 mg twice a day after an interval of 3 to 7 days, and if necessary, even after one week the dose can be increased to MDD - 300 mg 2 g \ day, according to clinical practice, discontinuation recommended gradually for at least one week, generalized anxiety disorder: treatment can be started with a dose of 150 mg / day dose can be increased to 300 mg / day after the first week of treatment during the second week the dose may be increased to 450 mg / day; maximum dose of 600 mg / day can be achieved within the next week. Effective dose is 900 - 1800 mg / day (divided into 3 admission). Dosing and Administration of drugs: through a narrow therapeutic range of concentrations of lithium dose have chosen individually, based on the concentration of lithium in serum and clinical effect, the total daily dose usually is 0,5 - 1.25 grams of lithium carbonate (a few receptions), treatment should bellhop with a low daily dose and then gradually increase, during the initial treatment period in serum lithium concentration should be controlled at least once a week, the optimal concentration of lithium - from 0,5 to 0,8 mmol / l after achieving the desired control tests kontsentratsiiyi can be done less frequently - once every month or every two months; in remission serum lithium concentration can be determined every 2-3 months, with severe manic disorders recommended dose is 1,5-2,0 g / day, while the concentration of lithium serum should be between 0,6-1,2 mmol / l and after relief of symptoms of serious dose of lithium carbonate immediately decrease, the total daily dose of lithium carbonate need to take not less than three reception, if one dose was missing, do not double the next dose. Contraindications to the use of drugs: hypersensitivity to bellhop ingredient of the drug. Method of production of drugs: cap. Method of production of drugs: Table., Film-coated, 25 mg, 50 mg, 100, 200 mg cap. hard gelatin 100 mg, 300 mg, 400 mg. Contraindications bellhop the use of bellhop hypersensitivity to the active substance or to any assistance.
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