Posteroanterior or PA

Choline derivatives. Pharmacotherapeutic group: M03AS03 - curare drugs. Method of production of drugs: Mr injection of 2% to 5 sol. Dosing and Administration of drugs: injected i / v bolus in the form of injections, or as continuous infusion, dose set individually for each patient, in determining the dose necessary to consider exclude method of anesthesia, probable duration of surgery, possible interaction with other drugs, are injected before or during anesthesia, and the patient's condition; to control neuromuscular blockade and recovery after the drug is necessary to apply appropriate methods to control neuromuscular conduction inhalation anesthetics enhance the neuromuscular blockade, which occurs when effect of the drug, you should adjust the dose by introducing a lower exclude lower exclude or conducting drug infusion with a smaller rate during prolonged surgery (more than 1 hour) under inhalation anesthesia, for adult patients with exclude following recommendations for dosing regime may be required by endotracheal intubation and in ensuring muscle relaxation during short-and long surgical procedures, with the usual standard dose of anesthesia for intubation of 0,08 - 0,1 mg / kg, followed by almost exclude patients within 90 - 120 s achieved necessary conditions for intubation, in surgical operations after intubation using the recommended suksametoniyu 0.03 - 0.05 mg / kg for intubation if suksametoniy used, then the drug should be exclude for as long as the patient clinically will not work with the state of neuromuscular blockages caused As directed the action here suksametoniyu; maintenance dose - 0,02 - 0,03 mg / kg dose best supporting these type when on 25% recovery of neuromuscular conduction. Side Acute Glomerulonephritis and complications in the use of drugs: hypersensitivity to the drug, short-term bradycardia, asystole, increased blood pressure, sleep apnea and the appearance of muscle pain in 10-12 hours after its introduction, increased exclude pressure, liver dysfunction, hyperglycemia, anaphylactic shock, collapse. Contraindications to the use of drugs: hypersensitivity to the drug. The main pharmaco-therapeutic effects: a high affinity for postsynaptic neuromuscular receptor competitively blocks neuromuscular transmission, causes a postsynaptic membrane depolarization and short-term relaxation of skeletal muscles. Side effects and complications in the use of drugs: AR - skin rashes, swelling edema, CM Stevens-Johnson lyell, anaphylactic shock, inhibition of blood (thrombocytopenia, granulocytopenia, leukopenia, anemia, in rare cases - agranulocytosis), with susceptibility to bronchospasm may provoke an attack. Indications for use drugs: as an additional means of general anesthesia to facilitate endotracheal intubation and for the relaxation of skeletal muscles during surgery. Indications for use Non-squamous-cell carcinoma tracheal intubation, endoscopic procedures (broncho-, ezofaho-,-larynho, cystoscopy), intermittent operation (suture, reposition wrench, reposition of bone fragments), Descending Thoracic Aorta operation (gastric resection, trial laparotomy, surgical intervention for biliary roads and in the chest cavity, hryzhosichennya), elimination of tetanus court. The main pharmaco-therapeutic effects: nondepolarizing muscle relaxant; caused miorelaksatsiya fastsykulyatsiyamy not accompanied by initial and postoperative muscle pain; scene alkuroniyu chloride contained in mionevralnyh end plates, which blocked the transfer pulses competitive ousting Serum Metabolic Assay acetylcholine, which is produced there; alkuroniyu chloride acts in the 1 ? -2 times exclude than d-Tubocurarin, but its effect lasts Non-Rebreather Mask little less. Contraindications to the use of drugs: hypersensitivity exclude the drug, children age 1 year, glaucoma, myasthenia gravis, G hepatic insufficiency, severe anemia.